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Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents.

Current protocols in pharmacology

Connolly DC, Hensley HH.
PMID: 20634901
Curr Protoc Pharmacol. 2009 Jun 01;45:14.12.1-14.12.26.

Epithelial ovarian cancer (EOC) is the most commonly fatal gynecologic malignancy in developed countries. Most EOC patients are diagnosed at advanced stage when disease has spread beyond the ovary. While many patients initially respond to surgery and chemotherapy, the...

Natural Products as a Foundation for Drug Discovery.

Current protocols in pharmacology

Beutler JA.
PMID: 20161632
Curr Protoc Pharmacol. 2009 Sep 01;46:9.11.1-9.11.21. doi: 10.1002/0471141755.ph0911s46.

Natural products have contributed to the development of many drugs for diverse indications. While most U.S. pharmaceutical companies have reduced or eliminated their in-house natural product groups, new paradigms and new enterprises have evolved to carry on a role...

Showing 1 to 2 of 2 entries